It has been said we are in a chronic disease epidemic of diabetes mellitus. Before COVID-19, approximately 10% of diabetes was juvenile Type 1, which is an auto-immune illness characterized by auto-antibodies against pancreatic islet cells. The remaining 90% is adult onset type 2 diabetes characterized by lifelong excess in adiposity and insulin resistance.
Mass vaccination with mRNA and adenoviral DNA vaccines may change the epidemiology of diabetes as we know it.
There are several papers emerging concerning new onset diabetes and diabetic ketoacidosis after taking a COVID-19 shot. Moon and colleagues reported a well characterized case of new onset type 1 diabetes in an adult temporally related to COVID-19 vaccination.
The rapid depletion of endogenous insulin (C-peptide) and detectable auto-antibodies suggests this new condition for the vaccine recipient will be permanent. This means lifelong insulin and glucose monitoring as a regrettable consequence of accepting a vaccine. This case and the others calls for a sweep of vaccine safety databases and clinical trials looking for hyperglycemia, diabetic ketoacidosis, and well-documented new onset diabetes. This will be only way for epidemiologists and diabetologists to develop risk stratification and detection methods. Because the auto-immune attack on the pancreas can be insidious and take time, I am concerned that months or years later the chronic disease epidemic of diabetes mellitus could be intensified by mass vaccination.
COVID-19 vaccine side effects that occur way less than one percent of the time can be a large problem for the community since nearly the entire population was duped or forced into vaccination. For so many reasons, any novel EUA vaccine campaign should be targeted on a small group at the highest risk so large numbers are not exposed to permanent side effects such as insulin-dependent type 1 diabetes.
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